ID: 176845
Approved: 19 June 2024
Principal investigator: Mr Aressi Rahman
Lead institution: University of Southampton
Other institutions: University of Xxxxxxxx, University of Yyyyyyy, University of Zzzzzzz
Last updated: 25 July 2024
Status: Status-code
Disease areas: Digestive system
Types of data: Biomarkers, Lifestyle
This 4-year PhD project aims to assess how healthy different commonly consumed fats are, with a focus on the impact on cardiovascular disease, cardiometabolic diseases such as type 2 diabetes, and inflammation and related diseases e.g arthritis. It is also aimed to develop a method that expresses this in a simple score. The need for this is due to different dietary fats having different health impacts, even within the same types or classes of fats. This makes generalised advice not very useful. An example is the advice to limit intake of saturated fats to mitigate the risk of developing cardiovascular disease despite that there are saturated fats that have a neutral or even positive impact on cardiovascular health. Also, as there are generally multiple different fats present within even one item of food it can difficult to make rational decisions. Accordingly, having a simple score, which could be displayed on packaging could help people make more healthy dietary decisions that could help mitigate disease risk.
There are various existing scoring systems that might be altered or a new method might be developed. Health related data from databases such as UK Biobank will be valuable in testing the accuracy of a method.
Publications from this project
Association of insomnia and daytime sleepiness with low back pain: A bidirectional mendelian randomization analysis
In Frontiers in Genetics
29 November 2022
Peng Shu, Lixian Ji, Zichuan Ping, Zhibo Sun, Wei Liu
Primary hypertension, anti-hypertensive medications and the risk of severe COVID-19 in UK Biobank
In PLOS One
9 November 2022
H Pavey et al
Exposure to various ambient air pollutants increases the risk of venous thromboembolism: A cohort study in UK Biobank
In Science of The Total Environment
1 November 2022
J Li et al